OpenVPX provides an effective method for describing VPX components, and also defines numerous “profiles” for boards, slots and backplanes that detail specific configurations of channels, interconnections and fabrics. Instead of starting from scratch each time, designers can browse through these standardized profiles to find one that satisfies the objectives of each new system. By narrowing the field of configurations, these profiles boost reusability and interoperability between vendors. OpenVPX presents a formal, well-organized system for defining all components in VPX systems, and the efforts of the working group should be applauded. Many of the figures and the profiles in this handbook were derived from the full OpenVPX specification. The OpenVPX specification is maintained by VITA as VITA 65.